Monday, 22 October, 2018

New Treatment For Fibroids Without Surgery

New Treatment For Fibroids Without Surgery

Posted on Friday, 10 November, 2017 by Zheluo Cai

New Treatment For Fibroids Without Surgery.

New Treatment For Fibroids Without Surgery — The location of fibroids in and around the uterus helps determine whether a woman is symptomatic, and how severe symptoms are. The location also determines if fertility is affected. ILLUSTRATION: ALAN WITSCHONKE

The first oral treatment for women with the common condition of uterine fibroids could be available as soon as summer 2018, with two other medications in the pipeline. The drugs, experts say, would provide a new treatment option for a condition most commonly treated with a hysterectomy, or removal of the uterus. “For the longest time we have not really had good options from an oral medication standpoint to treat fibroids,” says Arnold Advincula, vice chairman of women’s health and chief of gynaecology at Sloane Hospital for Women at NewYork-Presbysterian/Columbia University Medical Center. “It’s nice to have some additional tools in the toolbox.”

Earlier in October the U.S. Food and Drug Administration accepted Allergan ’s new drug application for ulipristal acetate (UA) to treat abnormal uterine bleeding caused by uterine fibroids. The company expects a decision by May. The drug has been available in Europe and Canada for several years. Two other oral medications indicated to treat uterine fibroids are also in development. Bayer launched a phase 3 clinical trial—usually the final trial used by regulators to decide whether to approve a drug—for a similar drug, vilaprisan, in the summer. And AbbeVie is in the midst of phase 3 trials for elagolix to treat uterine fibroids and endometriosis, a disorder in which the tissue that lines the inside of the uterus grows outside of it, causing pelvic pain. The company hopes to have a product available by 2020.

Credit: Sumathi Reddy for The Wall Street Journal 23 October 2017.

Tajik is a general designation for a wide range of native Persian-speaking people of Iranian origin, with current traditional homelands in present-day Tajikistan, Afghanistan and Uzbekistan. Not all Tajiks speak a variety of modern Persian. They may speak any one of the extant Iranian languages. For example, the Tajiks of China are actually Pamiris and speak the Eastern Iranian Pamiri languages and are distinct from more western Tajiks. They are concentrated in the Oxus Basin, the Farḡāna valley (Tajikistan and parts of Uzbekistan) and on both banks of the upper Oxus, i.e., the Pamir Mountains (Mountain Badaḵšān, in Tajikistan) and northeastern Afghanistan and western Afghanistan (Badaḵšān, Kābol, Herat, Balkh, Mazar-i-Sharif, Ghazni and other urban regions). Historically, the Tajiks were initially agriculturalists but urbanized rather early in ancient times as indicated by their role in the history of what later became Greater Khorasan. Several surviving ancient urban centres of the Tajik people include Herat, Samarkand, Bukhara, Khujand, and Kabul.

Young Stars in the Rho Ophiuchi Cloud.
Credit: NASA, JPL-Caltech, WISE Team. Dust clouds and embedded newborn stars glow at infrared wavelengths in this tantalizing false-colour composition from the Wide-field Infrared Survey Explorer. It is one of the closest star-forming regions of the Rho Ophiuchi cloud complex, some 400 light-years distant near the southern edge of the pronounceable constellation Ophiuchus. After forming along a large cloud of cold molecular hydrogen gas, young stars heat the surrounding dust to produce the infrared glow. Stars in the process of the formation called young stellar objects, are embedded in the compact pinkish nebulae. An exploration of the region in penetrating infrared light has detected emerging and newly formed stars whose average age is estimated to be a mere 300,000 years, which is extremely young compared to the Sun's age of 5 billion years. The prominent reddish nebula at the lower right surrounding the star Sigma Scorpii is a reflection nebula produced by dust scattering starlight. This view covers about 14 light-years at the estimated distance of the Rho Ophiuchi cloud.

The current flag of Myanmar was adopted on 21 October 2010. The new flag was introduced along with implementing changes to the country's name, which were laid out in the 2008 Constitution. The design of the flag has three horizontal stripes of yellow, green and red with a five-pointed white star in the middle. The three colours of the stripes are meant to symbolise solidarity, peace and tranquility, and courage and decisiveness. The white star that symbolised the Union of Burma.

The Elgin Marbles are a collection of Classical Greek marble sculptures made under the supervision of Phidias and his assistants in c. 447 to 438 BC; originally part of the temple of the Parthenon. From 1801 to 1812, agents of Thomas Bruce, 7th Earl of Elgin removed about half of the surviving sculptures and transported them to Britain. The half not removed is now displayed in the Acropolis Museum. In Britain, the acquisition of the collection was not supported by some, and the Earl's actions was likened to vandalism. Following a public debate in Parliament and its subsequent exoneration of Elgin, he sold the Marbles to the British government in 1816. They were then passed to the British Museum, where they are now on display in the purpose-built Duveen Gallery.

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