Scientists Unmask Superbug-Shielding Protein

Scientists Unmask Superbug-Shielding Protein.

Scientists in the University of Western Australia have mapped the molecular structure of a superbug’s protein that shields it against antibiotics. This is perhaps the first step in finding a way to disable the bacteria’s defense. The Centers for Disease Control and Prevention’s (CDC) latest Vital Signs report urges healthcare workers to use a combination of infection control recommendations to better protect patients from these infections. “New data show that far too many patients are getting infected with dangerous, drug-resistant bacteria in healthcare settings,” said CDC Director Tom Frieden, M.D., M.P.H. Many of the most urgent and serious antibiotic-resistant bacteria threaten patients while they are being treated in healthcare facilities for other conditions, and may lead to sepsis or death. In acute care hospitals, 1 in 7 catheter- and surgery-related HAIs can be caused by any of the six antibiotic-resistant bacteria listed below. That number increases to 1 in 4 infections in long-term acute care hospitals, which treat patients who are generally very sick and stay, on average, more than 25 days. The six antibiotic-resistant threats examined are:

  • Carbapenem-resistant Enterobacteriaceae (CRE)
  • Methicillin-resistant Staphylococcus aureus(MRSA)
  • ESBL-producing Enterobacteriaceae (extended-spectrum β-lactamases)
  • Vancomycin-resistant Enterococcus (VRE)
  • Multidrug-resistant Pseudomonas aeruginosa
  • Multidrug-resistant Acinetobacter

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http://www.bbc.com/news/world-australia-38977259